Stem cell treatment helping back pain patients
Your shoe should firmly hold your foot in place to keep you stable and protect your back, says Sinett, who also advises sticking to heels that are less than three inches high. Surprising Back Pain Causes, Cures Culprit No. 3: Your Beloved Smartphone or Tablet Mobile technology has not been kind to our backs and necks, Prather says. “We’re hovering over laptops, iPads, and smartphones all the time,” she notes. “This head-down position strains the muscles in the neck, and the pain can extend all the way down your spine to your lower back.” Take frequent breaks, and try to look straight aheadrather than downwhile using a laptop, tablet, or phone. You can buy a stand to help hold your laptop or tablet at a more back-friendly height and angle. Surprising Back Pain Causes, Cures Culprit No. 4: bayviewwellness Extra Pounds Carrying even just a few extra inches around your midsectionwhether it’s due to belly fat or pregnancymakes your pelvis tilt forward and out of alignment, as your body works to keep itself balanced. This can cause excessive strain on your lower back, Dr. Akuthota says.
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Back pain treatment often not in line with guidelines
Preclinical studies on sheep showed their discs were regenerated The treated disc looks exactly the same, you cant tell a difference at all and the untreated disc is very degenerative, very black, said McJunkin. Full human trial results will not be available until later this year, but in early data 71 percent of patients who received a low dose of stem cells showed a significant reduction in low back pain and improvement in function, compared with 20 percent of patients in the control group. Now, two years into the study Bobby says hes definitely feeling a difference and can’t wait for what’s next. Im thankful for that, truly, said Sydnor. Fifteen sites across the country are conducting the trials. Full results from the phase 2 trial are expected in the third quarter of this year. The stem cells do not come from human embryos. Instead, theyre harvested from healthy adult donors. Additional Information: Back pain affects 80 percent of Americans at some point in their lives. In fact, back pain problems are the most common physical complaints among American adults and are a leading cause of lost job time. It can include sore tendons and muscles, fractures, herniated discs, and other problems. The most common back pain causes include nerve and muscular problems, arthritis, and degenerative disc disease. It is important to understand that back pain is a symptom of a medical condition; it is not a diagnosis itself. (Source: http://www.webmd.com ) MEDICAL PROBLEMS: Medical problems that cause back pain can include: InjuriesSpine injuries, like fractures and sprains, can cause short-lived or chronic back pain. Sprains are tears in the ligaments that support the spine, and they occur from lifting improperly. Fractured vertebrae are often from osteoporosis. Accidents and falls are also causes of back pain. Mechanical ProblemsA mechanical problem is because of the way the spine moves or the way you feel when you move your spine in certain ways. One of the most common mechanical causes of back pain is a condition called intervertebral disc degeneration, meaning that the discs between the vertebrae of the spine are breaking down with age. (Source: http://www.webmd.com ) TREATMENT: Most back pain gets better with home treatment and careful attention. A short period of bed rest is recommended, but too many days can actually do more harm than good. When it is more severe, physical therapy is the cornerstone of back pain treatment. A physical therapist can apply a variety of treatments, like ultrasound, heat, electrical stimulation, and muscle-release techniques. If that doesnt work, injections are another option. The doctor may inject cortisone into the space around the spinal cord. (Source: http://www.mayoclinic.com ) NEW TECHNOLOGY: For some patients, traditional treatment just doesnt work. So, one of the newest breakthroughs in managing back pain is coming from stem cells. A company called Mesoblast released the latest news in a string of studies examining the ability of a specific type of stem cell to treat back pain. In the earliest tests, the company injected mesenchymal precursor cells (MPCs) into three adjacent lumbar discs in 24 adult male sheep. The sheep were injected with chrondroitinase in order to mimic disc degeneration and other discs were left alone. The degenerated discs had 45 to 50 percent less height before treatment with MPCs. After the discs were injected, they rehydrated and increased in height at statistically significant rates. Mesoblast has now released its second round of preliminary results from a phase 2 human study. For this phase, researchers injected allogeneic MPCs into damaged intervertebral discs. Researchers at IPM Medical Group in Walnut Creek, California; The Spine Institute in Santa Monica, California; Carolina Neurosurgery & Spine in Charlotte, North Carolina; Arizona Pain Specialists in Phoenix, Arizona; Virginia I-Spine acupuncture north york Physicians in Richmond, Virginia, and Emory Orthropaedics & Spine Center in Atlanta, Georgia, report that a single low-dose injection of MPC significantly reduced low back pain in the treated patients and did so at a statistically significant way when compared to the control group. The study has enrolled 100 patients in 13 sited in the U.S. and Australia. At the six month follow-up, 71 percent of patients who received a low dose of MPCs met the pre-specified treatment success criteria. Twenty and thirty percent of the patients in the two control arms who received hyaluronic acid and saline met the pre-specified success criteria. (Source: http://ryortho.com/breaking/major-study-update-stem-cells-ease-back-pain/ ) “Stem cell research within the disc is very exciting.
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Low back pain: physical therapy as the first choice
“We have increased utilization, yet we don’t have better treatment outcomes.” The American College of Physicians and the American Pain Society recommend that people with low back pain consider treatment with Tylenol or non-steroidal anti-inflammatory drugs (NSAIDs), as well as heating pads and exercise. The groups say doctors should only order CT and other scans when they suspect nerve damage. Opioids are only recommended for patients with “severe, disabling pain” that doesn’t get better with over-the-counter medicines – and their risks, such as for abuse and addiction, should be weighed against potential benefits. For the new study, Dr. Bruce Landon from the Harvard Medical School in Boston and his colleagues tracked nationally-representative data on outpatient visits for back and neck pain collected between 1999 and 2010. The researchers had information on about 24,000 visits, which represented a total of 440 million appointments across the U.S. During that span, they found the proportion of patients prescribed Tylenol and NSAIDs dropped from 37 percent to 25 percent. At the same time, the proportion given narcotics rose from 19 percent to 29 percent. About 11 percent of people with back pain had a CT or MRI scan in 2009 and 2010, compared to seven percent in 1999 and 2000. Finally, although the rate of referrals to physical therapy held steady during the study period, the proportion of patients referred to another doctor – likely for surgery or other treatments – doubled from seven to 14 percent, the researchers reported Monday in JAMA Internal Medicine. “Physicians want to offer patients treatments that are going to work sooner and patients are demanding them and sometimes it’s just easier to order the MRI or order the referral,” Landon said.
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Researchers from Aldo Moro University (AMU) in Italy found that supplementation with ALA in combination with both gamma linolenic acid (GLA), an omega-6 fatty acid, and physical rehabilitation helped alleviate symptoms of radicular neuropathy and restore normal function. After just six weeks of supplementing with 600 milligrams (mg) per day of ALA, in conjunction with 360 mg of GLA and regular exercise-based rehab, patients noticed significant improvements in their paresthesia symptoms, with far fewer sensations of burning and tingling on the skin. This same group reported drastic improvements in quality of life compared to another group treated only with exercise-based rehab. “Oral treatment with alpha lipoic acid (ALA) and gamma linolenic acid (GLA) for six weeks in synergy with rehabilitation therapy improved neuropathic symptoms and deficits in patients with radicular neuropathy,” reported the authors from AMU’s Physical Medicine and Rehabilitation Unit and Neurological and Psychiatric Sciences Departments. ALA also shown to help treat general lower back pain More recently, another study on ALA out of the University of Siena, also in Italy, found that the nutrient can help treat general lower back pain symptoms, regardless of their cause. A group of outpatients with varying lower back pain symptoms lasting longer than 12 weeks were given daily doses of ALA with much success. Somewhat similar to the earlier study, outpatients in this study were given a 60-day regimen of ALA at doses of 600 mg/day, in combination with doses of 140 international units (IU) per day of superoxide dismutase (SOD), a powerful antioxidant enzyme. Together, these two powerful nutrients led to a massive ninefold reduction in outpatients’s use of analgesics, or painkiller drugs. “[S]upplementation with alpha lipoic acid (600 mg/d) and superoxide dismutase (140 IU/d) for a period of 60 days was found to be associated with significantly reduced use of analgesics (8 percent of patients still used analgesics post-trial, as compared to 73.5 percent at baseline),” explains the study’s summary. “In addition, according to self-reporting tools, after 40 days of the intervention, perceived pain and functional disabilities significantly improved in a way that was both statistically and clinically significant.” ALA can also be administered intravenously for more potent results Chronic pain that results from any kind of nerve damage is admittedly very difficult to treat using conventional methods, primarily due to the fact that the actual source of pain may not appear to be at all related to where and how it is being manifested.
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Alpha lipoic acid (ALA) treats back pain naturally: Research
National Institute of Health reports that Americans spend at least $50 billion each year on low back pain, the most common cause of jobrelated disability and a leading contributor to missed work. These costs put a tremendous burden on the healthcare industry.The typical path a low back patient takes involves visits to multiple providers and includes radiological studies, painkillers, steroid injections and, in some cases, surgery. David Elton, senior vice president of Clinical Programs for Physical Medicine at OptumHealth, notes:When a back pain patients first visit is with a physical therapist  whose clinical decision making is aligned with current clinical evidence, the severity-adjusted total episode cost, including all treatment provided by any type of provider in any setting, is approximately 30 percent lower than the overall average total episode cost for treatment of back pain.Today, only 11 percent of back pain patients initial visit for treatment is with a physical therapist  whose treatment decisions are aligned with current clinical evidence. Helping more patients access treatment from  evidence-based conservative providers will not only result in better clinical outcomes, but will also save millions of dollars in direct medical expenses. In their research, Fritz, Julie, John Childs, and et al. from the university of Utah, have found that referral to a physical therapist for low back pain within 14 days of primary care consultation plays a role in reducing the risk of the need for subsequent health care utilization, including advanced imaging, additional doctor visits, major surgery, lumbar spine injections, and opioid medications. Results of this study suggest that early referral to PT has the potential to result in decreased subsequent healthcare utilization and overall costs when compared to delayed PT. Interestingly, these findings are consistent with a previous study consisting of Medicare beneficiaries, which collectively support early PT referral for LBP across multiple age groups despite guideline recommendations to delay PT referral. Michael Sheynin P.T. is co-owner of Free Motion Rehabilitation Center, 528 New Friendship Road, Howell. For more information, call 732-901-8844.
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